Research activities

Applied Research

Search for biologically active substances of synthetic and natural origin, the studying of their physicochemical properties and biological activity.

Lecturers and postgraduate students of the department conduct research in the general departmental direction "Search for biologically active substances of synthetic and natural origin, the studying of their physicochemical properties and biological activity".

Government grants

The lecturers of the department fulfilled the government grants: 6/06 "Synthesis of biologically active substances based of N- and S-substituted sulfur-containing amino acids and their analogues" (2006-2008, Head – Professor L.O. Omelyanchik). Today the department realizes the research "Rational design of S,N-modified amino-thiols as potential anti-radiation agents (No. 0119U000226) under the guidance of Associate Professor Kornet M.M. Scientific researches on synthesis, computer prediction and study of physicochemical and biological properties of derivatives of six-membered nitrogen-containing heterocycles are performed on the basis of the Laboratory of Biotechnology of Physiologically Active Substances (Head of the Laboratory – Professor O.A. Brazhko).

Scientific articles in Scopus and Web of Science

• Brazhko O.A., Yevlash A.S., Zavgorodnii M.P., Kornet M.M., Brazhko O.O., Lagron A.V. Basic approaches to the synthesis of pyrrolo[1,2-a]quinolines derivatives: a review. Voprosy khimii i khimicheskoi tekhnologii. 2019, No. 6, Р. 6-16. (Scopus).
• Tkach V.V., De Oliveira S.C., Kushnir M.V., Brazhko O.A., e Gala H.B., Luganska O.V., Yagodynets P.I. A descrição matemática do desempenho eletroanalítico do compósito poli(alaranjado da acridina)-oxihidróxido de vanádio na detecção eletrorredutiva da entacapona. The Revista Colombiana de Ciencias Químico – Farmacéuticas. 2019. Т. 48. № 2. C. 455-466. (Web of Science – SciELO Citation Index).
• Murlykina M.V., Kolomiets O.V., Kornet M.M., Sakhno Y.I., Desenko S.M., Dyakonenko V.V., Brazhko O.А. Doebner-type pyrazolopyridine carboxylic acids in an Ugi four-component reaction. Beilstein Journal of Organic Chemistry. 2019. № 15. Р. 1281-1288. (Scopus, Web of Science)
• Lashko N., Chausovsky G., Derevianko N., Brazhko O. Effect of light on the kinetics of oxidation reactions in vegetable oils. Food Science and Technology. 2019. Т. 13. № №3. C. 54-62. (Web of Science)
• Martynenko Y.V., Antypenko O.M., Brazhko O.A., Labenska I.B., Kovalenko S.I. Directed search of biologically active compounds among hydrogenated isoindolylalkyl(alkylaryl-,aryl-)carboxylic acids with quinazoline fragment that modify the Carbohydrate Metabolism: Design, synthesis and modification. Acta Chimica Slovenica. 2019. Vol. 66 (1). Р. 145-154. (Scopus, Web of Science)
• Hryhoriev S., Petryshchev A., Sinyaeva N., Yurchenko A., Kvitka S., Borisov V., Vlasiuk V., Tsymbal B., Borisova S. Studying the physical-chemical properties of alloyed metallurgical waste as secondary resource saving raw materials. Eastern-European Journal of Enterprise Technologies. 2018. № 4/12 (94). P. 43-48. (Scopus)
• Tkach V.V., Ivanushko Ya.G., Lukanova S.M., Kushnir M.V., de Oliveira S.C., Ojani R., Luganska O.V., Yagodynets ́ P.I. Evaluación teórica del desempeño del electrodo, modificado por el oxihidróxido de cobalto (III) en la detección del ácido úrico. Revista Colombiana de Ciencias Químico-Farmaceuticas. 2018. Vol. 47(2). Р. 289-300. (Web of Science – SciELO Citation Index)
• Tkach V.V., Ivanushko Ya.G., Lukanova S.M., Romaniv L.V., de Oliveira S.C., Ojani R., Luganska O.V., Yagodynets ́ P.I. A descrição matemática da análise eletroquímica do fármaco hidroxizina em soluções ácidas sobre um ácido sulfônico, baseado num polímero condutor. Revista Colombiana de Ciencias Químico-Farmaceuticas. 2018. Vol. 47(2). Р. 121-133. (Web of Science – SciELO Citation Index)
• Hryhoriev S., Petryshchev A., Shyshkanova G., Zaytseva T., Frydman O., Petrusha Yu., Andreev A., Katschan A., Lazutkin M., Sinyaeva N. Determining the patterns of phase and structural transformations at carbonthermal reduction of molybdenum concentrate. Eastern-European Journal of Enterprise Technologies. 2018. № 2/12 (92). P. 27-32. (Scopus)
• Hryhoriev S., Petryshchev A., Shyshkanova G., Zaytseva T., Frydman O., Krupey K., Andreev A., Katschan A., Petrusha Y., Dmytro Stepanov. A study of environmentally friendly recycling of technogenic chromium and nickel containing waste by the method of solid phase extraction. Eastern-European Journal of Enterprise Technologies. 2018. № 1/10 (91). P. 44-49. (Scopus)
• Karpenko Y.V., Omelyanchik L.O., Samura О.А., Omelyanchik V.N. Synthesis and study of the «acute toxicity vs. Structure» dependence of new hybrid 1,3,4-oxadiazole-2-thione with acridine-9(10h)-one. Voprosy Khimii i Khimicheskoi Tekhnologii. 2018. № 4. Р. 5-13. (Scopus)
• Karpenko Y.V., Omelyanchyk L.O., Panasenko T.V., Kuchmenko A.R. Chromatographic evaluation of the lipophilic properties of some derivated acridin-9(10h)-one. Methods and Objects of Chemical Analysis. 2018. № 13(3). Р. 115-120. (Scopus)
• Karpenko Y., Omelyanchik L., Panasenko T. Experimental and theoretical spectroscopic study of thione-thiol tautomerism of new hybrides 1,3,4-oxadiazole-2-thion with acridine-9(10h)-one. Chemistry and Chemical Technology. 2018. № 12(4). Р. 419-428. (Scopus, Web of Science)
• Karpenko Y.V., Omelyanchyk L.A. Studying the kinetics of liquid phase hydrazinolysis butyl 2-(2R-9-oxoacridine-10(9H)-yl)acetates. Journal of Chemistry and Technologies. 2018. № 26(1). Р. 31-39. (Scopus)
• Лашко Н.П., Дерев’янко Н.П., Дударєва Г.Ф. Binding of aromaforming krio- and thermotropic jelly of gelatin and starch Chemistry and chemical technology. 2017. Is. 11, № 4. P. 480-486. (Scopus)
• Murlykina M.V., Kornet M.N., Desenko S.M., Shishkina S.V., Shishkin O.V., Brazhko A.A., Musatov V.I., Van der Eycken E.V., Chebanov V.A. New tricks of well-known aminoazoles in isocyanide-based multicomponent reactions and antibacterial activity of the compounds synthesized. Beilstein Journal of Organic Chemistry. 2017. Vol. 13. Р. 1050-1063. (Scopus, Web of Science)
• Омельянчик Л.О., Синяєва Н.П., Луганська О.В., Пряхіна В.М., Курченко Л.Г. Визначення легуючих елементів у сталях та сплавах атомно-адсорбційним методом з високоінтенсивним джерелом випромінювання неперервного спектру. Український хімічний журнал. 2016. №5-6. С. 28-33. (Scopus)
• Рыльский А.Ф., Домбровский К.О., Крупей К.С., Петруша Ю.Ю. Биологическая очистка ливневых сточных вод промышленного предприятия иммобилизованными микроорганизмами и гидробионтами. Химия и технология воды. 2016. Т. 28, № 4. С. 420-430. (Scopus)

Scientific work of students

Students are actively involved in the scientific work of the department. There are student extracurricular activities at the department (on scientific problems, which are studied by the teaching staff). In the 2015-2019 academic years, students co-authored over 285 publications. There is Association of Young Scientists at the Faculty, where studies are conducted in all areas of scientific activity of the departments.

Under the direction of the department scientists, it is carried out the preparation of scientific student competition works, the level of that works has been repeatedly highly evaluated at various All-Ukrainian and regional scientific events. Students of the specialty 102 "Chemistry" (branch - 10 "Natural sciences") in 2015-2019 actively participated in the conference "Молода наука ", which was held by the student community of the Faculty of ZNU, annually participate in the scientific university conference and the competition "The best expert in chemistry". We should mark the achievements of the students of the chemistry department: in February 2017, 3rd year student Tetyana Tyurina won the annual All-Ukrainian competition for inventive and innovative projects of ecological and naturalistic fields (diploma for the 1st place in the category "Medicine and Health"); Master Teplova Yana achieved the Certificate of Excellence in student research during 2016-2017 and in competition of Science Day (May 2017); in 2018, the 2nd year student Danylo Maslov reached the Diploma of the winner of the All-Ukrainian Biological Forum of Student "Touch of Nature"; Master Alla Kuchmenko has won the 2nd place based the results of the European Project Activity Fundamentals course within the European Erasmus Program under the direction of J. Monet European Project Culture (EUOPROC) (2018); the 4th year student Eugeniia Vladova achieved a Certificate of Excellence in research during 2017-2018 and Science Day (2018).